Epidemics have marked and configured human communities for over 10,000 years. Professor Garrett will remind us of how living in groups means we infect but also immunize one another, a cycle that never ends. Current advances in transportation, the rise of mega cities, and the dynamics of a global economy now accelerate the cycle and pose new challenges. Professor Garrett will survey contemporary strategies for coping with infectious diseases such as Ebola and Zika and compare them to the ravages of Bubonic Plague, cholera, and influenza in the past. Stir in resistance to science in some cultural realms and the perils modern epidemics pose in our 21st century borderless world are grave indeed.